| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DR95_2398 | cls | DR95_2398 | DR95_967 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.906 |
| DR95_2398 | fimA_4 | DR95_2398 | DR95_3422 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | Fimbrial family protein. | 0.573 |
| DR95_2398 | hisA | DR95_2398 | DR95_1451 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | 0.608 |
| DR95_2398 | hisB | DR95_2398 | DR95_1449 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | Histidine biosynthesis bifunctional protein hisB; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.718 |
| DR95_2398 | hisD | DR95_2398 | DR95_1447 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.585 |
| DR95_2398 | hisE | DR95_2398 | DR95_1453 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | histidine_hisI: phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.938 |
| DR95_2398 | hisF | DR95_2398 | DR95_1452 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.745 |
| DR95_2398 | hisH | DR95_2398 | DR95_1450 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.643 |
| DR95_2398 | pgpB | DR95_2398 | DR95_937 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | PAP2 superfamily protein. | 0.926 |
| DR95_2398 | pgsA | DR95_2398 | DR95_577 | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.906 |
| cls | DR95_2398 | DR95_967 | DR95_2398 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | 0.906 |
| cls | pgpB | DR95_967 | DR95_937 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | PAP2 superfamily protein. | 0.914 |
| cls | pgsA | DR95_967 | DR95_577 | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.623 |
| fimA_4 | DR95_2398 | DR95_3422 | DR95_2398 | Fimbrial family protein. | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | 0.573 |
| hisA | DR95_2398 | DR95_1451 | DR95_2398 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein. | 0.608 |
| hisA | hisB | DR95_1451 | DR95_1449 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | Histidine biosynthesis bifunctional protein hisB; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.999 |
| hisA | hisD | DR95_1451 | DR95_1447 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.995 |
| hisA | hisE | DR95_1451 | DR95_1453 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | histidine_hisI: phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.999 |
| hisA | hisF | DR95_1451 | DR95_1452 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.999 |
| hisA | hisH | DR95_1451 | DR95_1450 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.999 |