Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ptsPPTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family. (748 aa)    
Predicted Functional Partners:
ptsO
Phosphocarrier protein NPr.
  
 
 0.997
rppH
RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
    0.843
ptsN
nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN.
  
   
 0.835
ptsH
Phosphocarrier protein HPr.
  
 
 
 0.833
crr
Glucose-specific phosphotransferase enzyme IIA component.
 
   
 0.784
arcB
Aerobic respiration control sensor protein ArcB.
   
 
 0.679
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.651
thyA
Thym_sym: thymidylate synthase.
     
 0.600
dhaM
PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM.
  
 
 
0.549
thiQ
Thiamine ABC transporter, ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
       0.443
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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