| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gidB | gyrA | DR95_3185 | DR95_225 | 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.710 |
| gidB | rpoB | DR95_3185 | DR95_2762 | 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.620 |
| gidB | tcdA | DR95_3185 | DR95_2467 | 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | thiF family protein. | 0.475 |
| gyrA | gidB | DR95_225 | DR95_3185 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.710 |
| gyrA | rpoB | DR95_225 | DR95_2762 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.796 |
| gyrA | tcdA | DR95_225 | DR95_2467 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | thiF family protein. | 0.477 |
| mltA | tcdA | DR95_2466 | DR95_2467 | Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | thiF family protein. | 0.574 |
| moeB | tcdA | DR95_1475 | DR95_2467 | moeB: molybdopterin synthase sulfurylase MoeB. | thiF family protein. | 0.430 |
| moeB | thiG | DR95_1475 | DR95_2767 | moeB: molybdopterin synthase sulfurylase MoeB. | Thiazole biosynthesis ThiG family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.895 |
| rpoB | gidB | DR95_2762 | DR95_3185 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.620 |
| rpoB | gyrA | DR95_2762 | DR95_225 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.796 |
| rpoB | tcdA | DR95_2762 | DR95_2467 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | thiF family protein. | 0.408 |
| rpoB | tmcA | DR95_2762 | DR95_485 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | tRNA(Met) cytidine acetyltransferase TmcA; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.740 |
| rpoB | tpiA | DR95_2762 | DR95_3060 | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.403 |
| tcdA | gidB | DR95_2467 | DR95_3185 | thiF family protein. | 16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.475 |
| tcdA | gyrA | DR95_2467 | DR95_225 | thiF family protein. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.477 |
| tcdA | mltA | DR95_2467 | DR95_2466 | thiF family protein. | Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. | 0.574 |
| tcdA | moeB | DR95_2467 | DR95_1475 | thiF family protein. | moeB: molybdopterin synthase sulfurylase MoeB. | 0.430 |
| tcdA | rpoB | DR95_2467 | DR95_2762 | thiF family protein. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.408 |
| tcdA | thiF | DR95_2467 | DR95_2769 | thiF family protein. | thiF family protein. | 0.421 |