| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DR95_2477 | glpG | DR95_2477 | DR95_2638 | tRNA pseudouridine synthase C family protein. | Rhomboid family protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.454 |
| DR95_2477 | nfuA | DR95_2477 | DR95_2640 | tRNA pseudouridine synthase C family protein. | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.572 |
| DR95_2477 | ptsG | DR95_2477 | DR95_2479 | tRNA pseudouridine synthase C family protein. | PTS system glucose-specific EIICB component. | 0.406 |
| DR95_2477 | thiI | DR95_2477 | DR95_1823 | tRNA pseudouridine synthase C family protein. | tRNA sulfurtransferase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.541 |
| DR95_2477 | topA | DR95_2477 | DR95_944 | tRNA pseudouridine synthase C family protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.437 |
| DR95_2477 | truC | DR95_2477 | DR95_2478 | tRNA pseudouridine synthase C family protein. | RNA pseudouridylate synthase family protein. | 0.875 |
| DR95_2477 | ygfY | DR95_2477 | DR95_2949 | tRNA pseudouridine synthase C family protein. | Flavinator of succinate dehydrogenase family protein. | 0.486 |
| DR95_2477 | yhcB | DR95_2477 | DR95_1968 | tRNA pseudouridine synthase C family protein. | Putative cytochrome d ubiquinol oxidase subunit 3. | 0.421 |
| DR95_2477 | zipA | DR95_2477 | DR95_124 | tRNA pseudouridine synthase C family protein. | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.420 |
| glpG | DR95_2477 | DR95_2638 | DR95_2477 | Rhomboid family protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | tRNA pseudouridine synthase C family protein. | 0.454 |
| glpG | nfuA | DR95_2638 | DR95_2640 | Rhomboid family protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.659 |
| nfuA | DR95_2477 | DR95_2640 | DR95_2477 | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | tRNA pseudouridine synthase C family protein. | 0.572 |
| nfuA | glpG | DR95_2640 | DR95_2638 | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Rhomboid family protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.659 |
| nfuA | thiI | DR95_2640 | DR95_1823 | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | tRNA sulfurtransferase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.614 |
| nfuA | topA | DR95_2640 | DR95_944 | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.529 |
| nfuA | ygfY | DR95_2640 | DR95_2949 | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Flavinator of succinate dehydrogenase family protein. | 0.533 |
| nfuA | zipA | DR95_2640 | DR95_124 | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.562 |
| ptsG | DR95_2477 | DR95_2479 | DR95_2477 | PTS system glucose-specific EIICB component. | tRNA pseudouridine synthase C family protein. | 0.406 |
| ptsG | truC | DR95_2479 | DR95_2478 | PTS system glucose-specific EIICB component. | RNA pseudouridylate synthase family protein. | 0.406 |
| thiI | DR95_2477 | DR95_1823 | DR95_2477 | tRNA sulfurtransferase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | tRNA pseudouridine synthase C family protein. | 0.541 |