Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
pckApckA: phosphoenolpyruvate carboxykinase. (423 aa)    
Predicted Functional Partners:
pckA_2
Phosphoenolpyruvate carboxykinase family protein; Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     0.988
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 
 0.941
gltA
cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 
 0.937
pyk
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.925
pyk-2
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.925
ppc
Phosphoenolpyruvate carboxylase family protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.925
pyk-3
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.925
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.918
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.913
aspA
aspA: aspartate ammonia-lyase.
   
 
  0.903
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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