Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DR95_2566Fdh-alpha: formate dehydrogenase, alpha subunit. (722 aa)    
Predicted Functional Partners:
fdoI
formate-DH-gamm: formate dehydrogenase, gamma subunit.
  
 
 0.957
hyfG
Hydrogenase-4 component G.
 
 
 0.936
fdoG_1
Molybdopterin oxidoreductase Fe4S4 domain protein.
 
 
  0.934
fdxH
Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
  
 
 0.932
fhs
Formate--tetrahydrofolate ligase family protein; Belongs to the formate--tetrahydrofolate ligase family.
     
 0.906
fdoG_2
formate-DH-alph: formate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 
0.904
fghA
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
    
  0.903
fdhF_1
Fdh-alpha: formate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 
0.901
norW
Nitric oxide reductase FlRd-NAD(+) reductase; Belongs to the FAD-dependent oxidoreductase family.
    
 0.899
cysJ_2
Sulfite reductase [NADPH] flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family.
    
 0.886
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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