STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chbRHTH-type transcriptional regulator ChbR. (282 aa)    
Predicted Functional Partners:
celB
PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
  
 0.886
chbA
N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIA component.
 
    0.833
chbG
ydjC-like family protein; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6- [...]
 
   
 0.785
chbB
N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component.
 
   
 0.709
flgG
flgG_G_neg: flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family.
    
   0.697
chbF
6-phospho-beta-glucosidase.
 
  
 0.691
nadR
Trifunctional NAD biosynthesis/regulator protein NadR.
  
  
 0.686
chiP
Outer membrane porin, OprD family protein.
  
     0.609
leuO
Putative HTH-type transcriptional regulator leuO; Belongs to the LysR transcriptional regulatory family.
  
  
 0.576
cobB
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
  
  
 0.566
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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