Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ttrSHis Kinase A domain protein. (587 aa)    
Predicted Functional Partners:
ttrR
Bacterial regulatory s, luxR family protein.
 
 0.998
ttrC
Polysulfide reductase, NrfD family protein.
 
   
 0.944
ttrA
Molybdopterin oxidoreductase Fe4S4 domain protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.915
arcB
Aerobic respiration control sensor protein ArcB.
  
 
 0.815
tmoT
Bacterial regulatory s, luxR family protein.
 
 
 0.810
rcsC
Sensor kinase protein RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
  
 
 0.764
ttrB
4Fe-4S dicluster domain protein.
 
   
 0.752
rcsD
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein.
 
 
 0.744
flgD
Basal-body rod modification protein flgD; Required for flagellar hook formation. May act as a scaffolding protein.
   
    0.703
flgD-2
Basal-body rod modification protein flgD.
   
    0.703
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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