gmk protein (Proteus vulgaris) - STRING interaction network

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Score

gmk

Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)

Predicted Functional Partners:

rpoZ

0.972

guaA

0.967

spoT

0.961

apt

0.944

gpt

0.944

hpt

0.941

ndk

0.929

pyk

0.927

pyk-2

0.924

pyk-3

0.922

Your Current Organism:

Proteus vulgaris

NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
apt	gmk	DR95_1783	DR95_2689	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.944
apt	gpt	DR95_1783	DR95_3627	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.	0.934
apt	guaA	DR95_1783	DR95_499	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	0.989
apt	hpt	DR95_1783	DR95_1754	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	HGPRTase: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.924
gmk	apt	DR95_2689	DR95_1783	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.944
gmk	gpt	DR95_2689	DR95_3627	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.	0.944
gmk	guaA	DR95_2689	DR95_499	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	0.967
gmk	hpt	DR95_2689	DR95_1754	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	HGPRTase: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.941
gmk	ndk	DR95_2689	DR95_99	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Nucleoside diphosphate kinase.	0.929
gmk	pyk	DR95_2689	DR95_1023	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.	0.927
gmk	pyk-2	DR95_2689	DR95_2357	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.	0.924
gmk	pyk-3	DR95_2689	DR95_740	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.	0.922
gmk	rpoZ	DR95_2689	DR95_2688	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.972
gmk	spoT	DR95_2689	DR95_2687	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Bifunctional (p)ppGpp synthase/hydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.961
gpt	apt	DR95_3627	DR95_1783	Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.934
gpt	gmk	DR95_3627	DR95_2689	Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.944
gpt	guaA	DR95_3627	DR95_499	Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.	GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	0.989
gpt	hpt	DR95_3627	DR95_1754	Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.	HGPRTase: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.924
guaA	apt	DR95_499	DR95_1783	GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.989
guaA	gmk	DR95_499	DR95_2689	GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.967

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