Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pilE1Hypothetical protein; IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain protein. (147 aa)    
Predicted Functional Partners:
gspE
Type II/IV secretion system family protein.
 
  
 0.837
epsF
Type II secretion system (T2SS), F family protein.
 
   
 0.825
pilQ
Bacterial type II and III secretion system family protein.
 
   
 0.763
gspO
Type IV leader peptidase family protein; Belongs to the peptidase A24 family.
 
   
 0.592
DR95_105
Tetratricopeptide repeat family protein.
  
     0.570
ampD
1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD.
     
 0.528
zapD
Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
 
     0.524
DR95_3059
Hypothetical protein.
  
     0.480
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.462
tfoX
tfoX N-terminal domain protein.
  
   
 0.449
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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