Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pdhRPyruvate dehydrogenase complex repressor. (256 aa)    
Predicted Functional Partners:
pdhR_2
Bacterial regulatory s, gntR family protein.
 
     0.695
glcA
Transporter, lactate permease family protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
  
 0.680
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 0.586
nadR
Trifunctional NAD biosynthesis/regulator protein NadR.
   
    0.538
fadR
Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism.
  
   
 0.532
aceF
Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  
 0.517
DR95_2078
Dihydroorotate dehydrogenase family protein.
  
  
 0.502
yidP
Hypothetical protein.
  
    0.473
ydfH
Bacterial regulatory s, gntR family protein.
 
  
 0.445
DR95_2775
Hypothetical protein.
  
     0.441
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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