STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppcPhosphoenolpyruvate carboxylase family protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (878 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 
 0.946
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.
   
 
 0.946
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.925
pckA
pckA: phosphoenolpyruvate carboxykinase.
     
 0.925
pyk
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.912
pyk-2
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.912
pyk-3
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.912
gltB
Glutamine amidotransferases class-II family protein.
 
  
 0.907
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.897
gltA
cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family.
     
 0.874
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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