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query proteins and first shell of interactors
white nodes:
second shell of interactors
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filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
metBO_succ_thio_ly: O-succinylhomoserine (thiol)-lyase. (386 aa)    
Predicted Functional Partners:
metL
Bifunctional aspartokinase/homoserine dehydrogenase 2; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.991
metA
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
 
 
 0.986
metF
Fadh2: 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.968
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.959
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.955
cysK
cysK: cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.954
metC
cysta_beta_ly_B: cystathionine beta-lyase.
  
 
 
0.954
metC-2
cysta_beta_ly_B: cystathionine beta-lyase.
  
 
 
0.954
patB_1
C_S_lyase_PatB: C-S lyase family protein.
 
 
 0.930
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
 
 0.927
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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