mdh protein (Proteus vulgaris) - STRING interaction network

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[Homology]

Score

mdh

Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)

Predicted Functional Partners:

gltA

0.997

fumC

0.992

maeB

0.977

maeA

0.956

ppc

0.946

fadJ

0.939

aceB

0.938

aspC

0.936

fadB

0.925

pckA

0.918

Your Current Organism:

Proteus vulgaris

NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aceB	fadB	DR95_2152	DR95_3514	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.	0.481
aceB	fadJ	DR95_2152	DR95_151	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.481
aceB	fumC	DR95_2152	DR95_915	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.917
aceB	gltA	DR95_2152	DR95_1555	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family.	0.967
aceB	maeA	DR95_2152	DR95_1469	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	NAD-dependent malic enzyme.	0.915
aceB	maeB	DR95_2152	DR95_492	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	NADP-dependent malic enzyme.	0.976
aceB	mdh	DR95_2152	DR95_3274	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.	0.938
aceB	pckA	DR95_2152	DR95_2542	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	pckA: phosphoenolpyruvate carboxykinase.	0.830
aceB	ppc	DR95_2152	DR95_3040	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	Phosphoenolpyruvate carboxylase family protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.	0.858
aspC	fumC	DR95_1380	DR95_915	Aspartate aminotransferase.	Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.887
aspC	gltA	DR95_1380	DR95_1555	Aspartate aminotransferase.	cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family.	0.890
aspC	mdh	DR95_1380	DR95_3274	Aspartate aminotransferase.	Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate.	0.936
aspC	pckA	DR95_1380	DR95_2542	Aspartate aminotransferase.	pckA: phosphoenolpyruvate carboxykinase.	0.836
aspC	ppc	DR95_1380	DR95_3040	Aspartate aminotransferase.	Phosphoenolpyruvate carboxylase family protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.	0.562
fadB	aceB	DR95_3514	DR95_2152	Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.	malate_syn_A: malate synthase A; Belongs to the malate synthase family.	0.481
fadB	fadJ	DR95_3514	DR95_151	Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.	Fatty oxidation complex, alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.991
fadB	fumC	DR95_3514	DR95_915	Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.	Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.856
fadB	gltA	DR95_3514	DR95_1555	Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.	cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family.	0.911
fadB	maeA	DR95_3514	DR95_1469	Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.	NAD-dependent malic enzyme.	0.813
fadB	maeB	DR95_3514	DR95_492	Fatty oxidation complex, alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.	NADP-dependent malic enzyme.	0.917

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