STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyaAAdenylate cyclase, class-I family protein; Belongs to the adenylyl cyclase class-1 family. (864 aa)    
Predicted Functional Partners:
cpdA
Calcineurin-like phosphoesterase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.962
nrdD
nrdD: anaerobic ribonucleoside-triphosphate reductase.
  
  
  0.915
pyk
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
     
  0.900
mazG
Nucleoside triphosphate pyrophosphohydrolase.
     
  0.900
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
pyk-2
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
     
  0.900
spoT
Bifunctional (p)ppGpp synthase/hydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
pyk-3
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
     
  0.900
ndk
Nucleoside diphosphate kinase.
     
  0.900
folE
folE: GTP cyclohydrolase I.
     
  0.800
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.