STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fccBPyridine nucleotide-disulfide oxidoreductase family protein. (397 aa)    
Predicted Functional Partners:
metB
O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase.
   
  0.905
psrA
Polysulfide reductase chain A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.902
cysK
cysK: cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
  0.900
DR95_141
Prokaryotic cytochrome b561 family protein.
     
  0.900
ydhX_1
4Fe-4S dicluster domain protein.
     
  0.900
DR95_1851
Prokaryotic cytochrome b561 family protein.
     
  0.900
DR95_3386
Hypothetical protein.
  
    0.791
megL
Met_gam_lyase: methionine gamma-lyase.
  
   0.734
tusA
Sulfurtransferase tusA; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
 
   
 0.535
hybD
hupD: hydrogenase expression/formation protein.
    
 
 0.514
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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