STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hnsDNA-binding protein H-NS; A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome. As many horizontally transferred genes are AT-rich, it plays a central role in silencing foreign genes. A subset of genes are repressed by H-NS in association with other proteins (By similarity). (134 aa)    
Predicted Functional Partners:
ymoA
Modulating protein ymoA.
  
 
 0.960
lpp
Lipoleucine-zipper family protein.
  
    0.776
yhcB
Putative cytochrome d ubiquinol oxidase subunit 3.
  
     0.658
DR95_2482
Hypothetical protein; Belongs to the UPF0325 family.
  
    0.638
zapB
Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
    0.637
arcB
Aerobic respiration control sensor protein ArcB.
  
   
 0.601
yciS
Inner membrane protein yciS; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.
  
     0.596
dsbA
Thiol:disulfide interchange protein DsbA.
  
   
 0.592
ptsH
Phosphocarrier protein HPr.
   
    0.586
helD
Helicase IV.
  
 
   0.572
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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