Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
betITranscriptional repressor BetI; Repressor involved in choline regulation of the bet genes. (200 aa)    
Predicted Functional Partners:
betB
Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.
  
 0.986
betA
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
  
 0.982
betT_1
Bcct: transporter, betaine/carnitine/choline transporter family protein; Belongs to the BCCT transporter (TC 2.A.15) family.
 
  
 0.791
aldA
Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
 0.564
betT_2
Bcct: transporter, betaine/carnitine/choline transporter family protein; Belongs to the BCCT transporter (TC 2.A.15) family.
  
  
 0.539
mlr_2
FAD binding domain protein.
  
     0.490
mlr_1
FAD binding domain protein.
  
     0.458
polB
DNA polymerase family B, exonuclease domain protein.
  
     0.448
gabD
Succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family.
 
  
 0.442
proV
proV: glycine betaine/L-proline transport ATP binding subunit.
 
   
 0.419
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.