| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DR95_884 | ltaE | DR95_884 | DR95_883 | Hypothetical protein. | Beta-eliminating lyase family protein. | 0.477 |
| dnaK_1 | gltB | DR95_882 | DR95_1959 | Hydantoinase/oxoprolinase family protein. | Glutamine amidotransferases class-II family protein. | 0.446 |
| dnaK_1 | ltaE | DR95_882 | DR95_883 | Hydantoinase/oxoprolinase family protein. | Beta-eliminating lyase family protein. | 0.481 |
| gcvP | gltB | DR95_2946 | DR95_1959 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glutamine amidotransferases class-II family protein. | 0.900 |
| gcvP | glyA | DR95_2946 | DR95_83 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
| gcvP | ltaE | DR95_2946 | DR95_883 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Beta-eliminating lyase family protein. | 0.542 |
| gltB | dnaK_1 | DR95_1959 | DR95_882 | Glutamine amidotransferases class-II family protein. | Hydantoinase/oxoprolinase family protein. | 0.446 |
| gltB | gcvP | DR95_1959 | DR95_2946 | Glutamine amidotransferases class-II family protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.900 |
| gltB | glyA | DR95_1959 | DR95_83 | Glutamine amidotransferases class-II family protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.458 |
| gltB | ltaE | DR95_1959 | DR95_883 | Glutamine amidotransferases class-II family protein. | Beta-eliminating lyase family protein. | 0.453 |
| gltB | metL | DR95_1959 | DR95_3042 | Glutamine amidotransferases class-II family protein. | Bifunctional aspartokinase/homoserine dehydrogenase 2; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.708 |
| gltB | thrA | DR95_1959 | DR95_1906 | Glutamine amidotransferases class-II family protein. | Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.708 |
| glyA | gcvP | DR95_83 | DR95_2946 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.997 |
| glyA | gltB | DR95_83 | DR95_1959 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutamine amidotransferases class-II family protein. | 0.458 |
| glyA | ltaE | DR95_83 | DR95_883 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Beta-eliminating lyase family protein. | 0.432 |
| glyA | metL | DR95_83 | DR95_3042 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Bifunctional aspartokinase/homoserine dehydrogenase 2; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.547 |
| glyA | thrA | DR95_83 | DR95_1906 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.547 |
| ltaE | DR95_884 | DR95_883 | DR95_884 | Beta-eliminating lyase family protein. | Hypothetical protein. | 0.477 |
| ltaE | dnaK_1 | DR95_883 | DR95_882 | Beta-eliminating lyase family protein. | Hydantoinase/oxoprolinase family protein. | 0.481 |
| ltaE | gcvP | DR95_883 | DR95_2946 | Beta-eliminating lyase family protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.542 |