| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroE | guaA | DR95_2106 | DR95_499 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.740 |
| aroE | nuoC | DR95_2106 | DR95_197 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.740 |
| aroE | pheA | DR95_2106 | DR95_3596 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | P-protein. | 0.670 |
| aroE | trpA | DR95_2106 | DR95_958 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.563 |
| aroE | trpB | DR95_2106 | DR95_957 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.549 |
| aroE | trpC | DR95_2106 | DR95_956 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Indole-3-glycerol phosphate synthase family protein; Belongs to the TrpC family. | 0.714 |
| aroE | trpD | DR95_2106 | DR95_955 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.532 |
| aroE | trpE | DR95_2106 | DR95_953 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | trpE_proteo: anthranilate synthase component I. | 0.711 |
| aroE | trpG | DR95_2106 | DR95_954 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Anthranilate synthase component II. | 0.624 |
| aroE | trpG_2 | DR95_2106 | DR95_2727 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | trpG_papA: glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein. | 0.633 |
| guaA | aroE | DR95_499 | DR95_2106 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.740 |
| guaA | nuoC | DR95_499 | DR95_197 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.768 |
| guaA | pheA | DR95_499 | DR95_3596 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | P-protein. | 0.587 |
| guaA | trpA | DR95_499 | DR95_958 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.520 |
| guaA | trpB | DR95_499 | DR95_957 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.511 |
| guaA | trpC | DR95_499 | DR95_956 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Indole-3-glycerol phosphate synthase family protein; Belongs to the TrpC family. | 0.557 |
| guaA | trpD | DR95_499 | DR95_955 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.431 |
| guaA | trpE | DR95_499 | DR95_953 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | trpE_proteo: anthranilate synthase component I. | 0.685 |
| nuoC | aroE | DR95_197 | DR95_2106 | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.740 |
| nuoC | guaA | DR95_197 | DR95_499 | NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.768 |