STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycaOConserved hypothetical protein; Homologs of previously reported genes of unknown function. (586 aa)    
Predicted Functional Partners:
truD
Pseudoruidine synthase; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
      
 0.815
yliG
Putative AdoMet-dependent methyltransferase, UPF0004 family; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
  
  
 0.726
thiF
Thiamin (thiazole moiety) biosynthesis protein; Function experimentally demonstrated in the studied species; enzyme.
     
 0.667
rbbA
Fused ribosome-associated ATPase: ATP-binding protein; Function experimentally demonstrated in the studied species; enzyme.
  
  
 0.646
ydcW
Medium chain aldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme.
      
 0.645
ycfD
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.577
ycaP
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component.
     
 0.569
nfnB
Dihydropteridine reductase, NAD(P)H-dependent, oxygen-insensitive; Function experimentally demonstrated in the studied species; enzyme.
  
  
 0.521
nfsA
Nitroreductase A, NADPH-dependent, FMN-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the flavin oxidoreductase frp family.
  
  
 0.521
rutE
Oxidoreductase subunit of the alternative pyrimidine degradation pathway; May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted; Belongs to the nitroreductase family. HadB/RutE subfamily.
  
  
 0.521
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.