STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
efeUFerrous iron permease; Function of homologous gene experimentally demonstrated in an other organism; transporter. (279 aa)    
Predicted Functional Partners:
efeO
Ferrous iron transport binding protein; Function experimentally demonstrated in the studied species; transporter.
  
 0.998
efeB
Heme-binding periplasmic protein involved in iron transport; Function experimentally demonstrated in the studied species; transporter.
 
  
 0.968
yfeX
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.598
macB
Fused macrolide transporter subunits of ABC superfamily: ATP-binding component; Function experimentally demonstrated in the studied species; transporter.
  
  
 0.532
lolD
Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.
  
  
 0.531
fhuD
Iron-hydroxamate transporter subunit; Function experimentally demonstrated in the studied species; transporter.
   
  
 0.524
btuF
Vitamin B12 transporter subunit: periplasmic-binding component of ABC superfamily; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
   
  
 0.524
fhuC
Iron-hydroxamate transporter subunit; Function experimentally demonstrated in the studied species; transporter.
   
  
 0.504
fepC
Iron-enterobactin transporter subunit; Function experimentally demonstrated in the studied species; transporter.
   
  
 0.504
fiu
Putative TonB-dependent iron outer membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
  
 0.503
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.