STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdoCMembrane protein required for modification of periplasmic glucan; Function experimentally demonstrated in the studied species; membrane component. (385 aa)    
Predicted Functional Partners:
mdoB
Phosphoglycerol transferase I; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family.
  
  
 0.919
mdoG
Glucan biosynthesis protein, periplasmic; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
     
 0.807
mdoH
Glucan biosynthesis: glycosyl transferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
     
 0.788
yfhB
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.759
ypfN
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.757
yiaH
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component.
 
   
 0.757
ynfB
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0482 family.
  
     0.745
rcsD
Phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Function experimentally demonstrated in the studied species; regulator.
  
  
 0.741
yqjB
Conserved hypothetical protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
   
 0.740
aroM
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 3001025.
  
     0.735
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.