node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dapA | dapB | ECIAI1_2529 | ECIAI1_0032 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.997 |
dapA | dapF | ECIAI1_2529 | ECIAI1_4000 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.874 |
dapA | lysC | ECIAI1_2529 | ECIAI1_4249 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartokinase III; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aspartokinase family. | 0.775 |
dapA | metL | ECIAI1_2529 | ECIAI1_4149 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Fused aspartokinase II; Function experimentally demonstrated in the studied species; enzyme. | 0.956 |
dapA | thrA | ECIAI1_2529 | ECIAI1_0002 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Fused aspartokinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aspartokinase family. | 0.953 |
dapA | usg | ECIAI1_2529 | ECIAI1_2396 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Putative semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.796 |
dapB | dapA | ECIAI1_0032 | ECIAI1_2529 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.997 |
dapB | dapF | ECIAI1_0032 | ECIAI1_4000 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.897 |
dapB | lysC | ECIAI1_0032 | ECIAI1_4249 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Aspartokinase III; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aspartokinase family. | 0.717 |
dapB | metL | ECIAI1_0032 | ECIAI1_4149 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Fused aspartokinase II; Function experimentally demonstrated in the studied species; enzyme. | 0.555 |
dapB | thrA | ECIAI1_0032 | ECIAI1_0002 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Fused aspartokinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aspartokinase family. | 0.555 |
dapB | usg | ECIAI1_0032 | ECIAI1_2396 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Putative semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.560 |
dapF | dapA | ECIAI1_4000 | ECIAI1_2529 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.874 |
dapF | dapB | ECIAI1_4000 | ECIAI1_0032 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.897 |
dapF | gltB | ECIAI1_4000 | ECIAI1_3360 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Glutamate synthase, large subunit; Function experimentally demonstrated in the studied species; enzyme. | 0.678 |
dapF | metL | ECIAI1_4000 | ECIAI1_4149 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Fused aspartokinase II; Function experimentally demonstrated in the studied species; enzyme. | 0.405 |
dapF | thrA | ECIAI1_4000 | ECIAI1_0002 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Fused aspartokinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aspartokinase family. | 0.405 |
dapF | usg | ECIAI1_4000 | ECIAI1_2396 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Putative semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.635 |
dedA | pdxB | ECIAI1_2394 | ECIAI1_2397 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. | Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. | 0.457 |
dedA | truA | ECIAI1_2394 | ECIAI1_2395 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.641 |