STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
emrBMultidrug efflux system protein; Function experimentally demonstrated in the studied species; transporter; Belongs to the major facilitator superfamily. (512 aa)    
Predicted Functional Partners:
emrA
Multidrug efflux system; Function experimentally demonstrated in the studied species; transporter.
 
 0.999
tolC
Transport channel; Function experimentally demonstrated in the studied species; transporter.
  
 
 0.978
mprA
DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; Function experimentally demonstrated in the studied species; regulator.
 
   
 0.890
emrK
EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component; Function experimentally demonstrated in the studied species; transporter.
 
 
 0.886
mdtB
Multidrug efflux system, subunit B; Function experimentally demonstrated in the studied species; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 
 0.696
emrD
Multidrug efflux system protein; Function experimentally demonstrated in the studied species; transporter.
  
   
 0.686
cmr
Multidrug efflux system protein; Function experimentally demonstrated in the studied species; transporter.
      
 0.662
macB
Fused macrolide transporter subunits of ABC superfamily: ATP-binding component; Function experimentally demonstrated in the studied species; transporter.
   
 
 0.658
mdtK
Multidrug efflux system transporter; Function experimentally demonstrated in the studied species; transporter.
      
 0.645
acrD
Aminoglycoside/multidrug efflux system; Function experimentally demonstrated in the studied species; transporter.
   
 
 0.643
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.