STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yghWConserved hypothetical protein; Homologs of previously reported genes of unknown function. (95 aa)    
Predicted Functional Partners:
hybE
Hydrogenase 2-specific chaperone; Function experimentally demonstrated in the studied species; factor.
       0.778
hybD
Maturation element for hydrogenase 2; Function of strongly homologous gene; factor.
       0.778
hybC
Hydrogenase 2, large subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
       0.778
hybB
Function of strongly homologous gene; carrier.
       0.778
hybA
Hydrogenase 2 4Fe-4S ferredoxin-type component; Function experimentally demonstrated in the studied species; putative carrier.
       0.778
hybO
Hydrogenase 2, small subunit; Function experimentally demonstrated in the studied species; enzyme.
       0.778
hybF
Protein involved with the maturation of hydrogenases 1 and 2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
       0.773
CAQ99962.1
Conserved hypothetical protein; Doubtful CDS.
       0.773
hybG
Hydrogenase 2 accessory protein; Function experimentally demonstrated in the studied species; putative factor.
       0.760
htpY
Heat shock protein; Function experimentally demonstrated in the studied species; regulator.
      
 0.653
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.