STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrfDPutative pilus assembly protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (259 aa)    
Predicted Functional Partners:
yrfC
Putative fimbrial assembly protein (pilN-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
  
 
 0.982
hofQ
Fimbrial transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
 
 0.942
yrfB
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component.
  
  
 0.818
yrfA
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.801
ycaI
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component.
      
 0.648
ygcQ
Putative flavoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
      
 0.644
mrcA
Fused penicillin-binding protein 1a: murein transglycosylase; Function experimentally demonstrated in the studied species; enzyme.
     
 0.613
yijE
Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
      
 0.559
ppdD
Putative major pilin subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
     
 0.480
ygaU
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
    
   0.463
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.