STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sgbH3-keto-L-gulonate 6-phosphate decarboxylase; Function experimentally demonstrated in the studied species; enzyme. (220 aa)    
Predicted Functional Partners:
sgbU
Putative L-xylulose 5-phosphate 3-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.999
lyxK
L-xylulose kinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the FGGY kinase family.
 
  
 0.992
ulaE
L-xylulose 5-phosphate 3-epimerase; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization; Belongs to the L-ribulose-5-phosphate 3-epimerase family.
 
 
 0.985
ulaG
Putative L-ascorbate 6-phosphate lactonase; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions; Belongs to the UlaG family.
 
  
 0.979
sgbE
L-ribulose-5-phosphate 4-epimerase; Function experimentally demonstrated in the studied species; enzyme.
 
  
 0.971
ulaD
3-keto-L-gulonate 6-phosphate decarboxylase; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization. Belongs to the HPS/KGPDC family. KGPDC subfamily.
  
  
 
0.905
yiaO
Transporter; Function experimentally demonstrated in the studied species; transporter.
     
 0.815
yiaN
Transporter; Function experimentally demonstrated in the studied species; transporter.
     
 0.813
ulaB
L-ascorbate-specific enzyme IIB component of PTS; Function experimentally demonstrated in the studied species; transporter.
 
  
 0.794
ulaA
L-ascorbate-specific enzyme IIC component of PTS; Function experimentally demonstrated in the studied species; transporter.
 
   
 0.792
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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