STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grxCGlutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (83 aa)    
Predicted Functional Partners:
secB
Protein export chaperone; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
 0.963
yibN
Putative rhodanese-related sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.930
ydhD
Monothiol glutaredoxin; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.923
grxB
Glutaredoxin 2 (Grx2); Function experimentally demonstrated in the studied species; carrier.
      
 0.820
trxA
Function experimentally demonstrated in the studied species; carrier; Belongs to the thioredoxin family.
  
  
 0.712
gpsA
Glycerol-3-phosphate dehydrogenase (NAD+); Function experimentally demonstrated in the studied species; enzyme; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.702
nrdA
Ribonucleoside diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.662
nrdE
Ribonucleoside-diphosphate reductase 2, alpha subunit; Function experimentally demonstrated in the studied species; enzyme.
  
 0.662
gor
Glutathione oxidoreductase; Function experimentally demonstrated in the studied species; carrier.
  
 
 0.642
msrA
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 
 0.609
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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