STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcuSTwo-component system sensor histidine kinase DcuS; Function experimentally demonstrated in the studied species; regulator. (543 aa)    
Predicted Functional Partners:
dcuR
DNA-binding response regulator in two-component regulatory system with DcuS; Function experimentally demonstrated in the studied species; regulator.
 
 0.999
dcuB
C4-dicarboxylate antiporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
     
 0.893
citB
DNA-binding response regulator in two-component regulatory system with citA; Function experimentally demonstrated in the studied species; regulator.
 
 
 0.879
dctA
C4-dicarboxylic acid, orotate and citrate transporter; Function experimentally demonstrated in the studied species; transporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
 
   
 0.847
phoQ
Sensory histidine kinase in two-compoent regulatory system with PhoP; Function experimentally demonstrated in the studied species; regulator.
      
 0.646
narX
Sensory histidine kinase in two-component regulatory system with NarL; Function experimentally demonstrated in the studied species; regulator.
      
 0.646
yjdJ
Putative acyltransferase with acyl-CoA N-acyltransferase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.533
yjdI
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.520
citA
Sensory histidine kinase in two-component regulatory system with citB; Function experimentally demonstrated in the studied species; regulator.
  
 
 
0.440
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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