STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fhuFFerric iron reductase involved in ferric hydroximate transport; Function experimentally demonstrated in the studied species; carrier. (262 aa)    
Predicted Functional Partners:
tonB
Membrane spanning protein in TonB-ExbB-ExbD complex; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
  
 0.932
exbB
Membrane spanning protein in TonB-ExbB-ExbD complex; Function experimentally demonstrated in the studied species; membrane component.
   
  
 0.912
exbD
Membrane spanning protein in TonB-ExbB-ExbD complex; Function experimentally demonstrated in the studied species; membrane component.
   
  
 0.889
yncE
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.856
fhuA
Ferrichrome outer membrane transporter; Function experimentally demonstrated in the studied species; transporter.
 
  
 0.836
yieE
Putative phosphopantetheinyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.749
ypfG
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.745
mdoB
Phosphoglycerol transferase I; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family.
  
     0.709
fhuD
Iron-hydroxamate transporter subunit; Function experimentally demonstrated in the studied species; transporter.
 
  
 0.703
aroM
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 3001025.
  
     0.679
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.