STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ibrBImmunoglobulin-binding regulator; Function of strongly homologous gene; regulator. (209 aa)    
Predicted Functional Partners:
ibrA
Immunoglobulin-binding regulator; Function of strongly homologous gene; regulator.
 
 
 0.997
bcsA
Fragment of cellulose synthase, catalytic subunit (part 1); Gene remnant; enzyme.
  
 
 0.924
gidB
Methyltransferase, SAM-dependent methyltransferase, glucose-inhibited cell-division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
  
  
 0.833
polA
Fused DNA polymerase I 5'->3' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.542
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
     
 0.528
ybdL
Methionine aminotransferase, PLP-dependent; Function experimentally demonstrated in the studied species; enzyme.
  
  
 0.514
ybdO
Putative DNA-binding transcriptional regulator, LysR-type; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family.
       0.509
ftsZ
GTP-binding tubulin-like cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.503
topA
DNA topoisomerase I, omega subunit; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus re [...]
  
  
 0.460
lepB
Leader peptidase (signal peptidase I); Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S26 family.
  
  
 0.433
Your Current Organism:
Escherichia coli UMN026
NCBI taxonomy Id: 585056
Other names: E. coli UMN026
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