STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fimZDNA-binding transcriptional regulator, isolated component of a two-component regulator system; Function experimentally demonstrated in the studied species; regulator. (210 aa)    
Predicted Functional Partners:
evgS
Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator.
 
 
 0.810
torS
Hybrid sensory histidine kinase in two-component regulatory system with TorR; Function experimentally demonstrated in the studied species; regulator.
 
 
 0.765
arcB
Hybrid sensory histidine kinase in two-component regulatory system with ArcA; Function experimentally demonstrated in the studied species; regulator.
 
 
 0.760
yhjB
Putative DNA-binding response regulator in two-component regulatory system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
     0.751
narX
Sensory histidine kinase in two-component regulatory system with NarL; Function experimentally demonstrated in the studied species; regulator.
 
 
 0.690
uhpB
Sensory histidine kinase in two-component regulatory sytem with UhpA; Function experimentally demonstrated in the studied species; regulator.
 
 
 0.683
narQ
Sensory histidine kinase in two-component regulatory system with NarP (NarL); Function experimentally demonstrated in the studied species; regulator.
 
 
 0.660
yegE
Putative diguanylate cyclase, GGDEF domain signalling protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.558
rcsC
Hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
 
 0.450
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.