node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAR18983.1 | CAR18984.1 | ECIAI39_2861 | ECIAI39_2862 | Putative fused protein: aminotransaminase/transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.764 |
CAR18983.1 | ycfQ | ECIAI39_2861 | ECIAI39_2049 | Putative fused protein: aminotransaminase/transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.435 |
CAR18984.1 | CAR18983.1 | ECIAI39_2862 | ECIAI39_2861 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Putative fused protein: aminotransaminase/transcriptional regulator, GntR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.764 |
CAR18984.1 | nrdE | ECIAI39_2862 | ECIAI39_2865 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.439 |
CAR18984.1 | nrdF | ECIAI39_2862 | ECIAI39_2866 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.441 |
CAR18984.1 | nrdH | ECIAI39_2862 | ECIAI39_2863 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Glutaredoxin-like protein; Function experimentally demonstrated in the studied species; putative carrier. | 0.478 |
CAR18984.1 | nrdI | ECIAI39_2862 | ECIAI39_2864 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Protein that stimulates ribonucleotide reduction; Probably involved in ribonucleotide reductase function. | 0.455 |
CAR18984.1 | nupG | ECIAI39_2862 | ECIAI39_3388 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Nucleoside transporter; Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force; Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family. | 0.406 |
CAR18984.1 | nupG-2 | ECIAI39_2862 | ECIAI39_2552 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Putative nucleoside transporter; Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force; Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family. | 0.406 |
CAR18984.1 | ybdK | ECIAI39_2862 | ECIAI39_0556 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Gamma-glutamyl:cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity. | 0.492 |
CAR18984.1 | ycfQ | ECIAI39_2862 | ECIAI39_2049 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.422 |
nrdE | CAR18984.1 | ECIAI39_2865 | ECIAI39_2862 | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.439 |
nrdE | nrdF | ECIAI39_2865 | ECIAI39_2866 | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.999 |
nrdE | nrdH | ECIAI39_2865 | ECIAI39_2863 | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Glutaredoxin-like protein; Function experimentally demonstrated in the studied species; putative carrier. | 0.996 |
nrdE | nrdI | ECIAI39_2865 | ECIAI39_2864 | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Protein that stimulates ribonucleotide reduction; Probably involved in ribonucleotide reductase function. | 0.999 |
nrdF | CAR18984.1 | ECIAI39_2866 | ECIAI39_2862 | Ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.441 |
nrdF | nrdE | ECIAI39_2866 | ECIAI39_2865 | Ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
nrdF | nrdH | ECIAI39_2866 | ECIAI39_2863 | Ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Glutaredoxin-like protein; Function experimentally demonstrated in the studied species; putative carrier. | 0.994 |
nrdF | nrdI | ECIAI39_2866 | ECIAI39_2864 | Ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Protein that stimulates ribonucleotide reduction; Probably involved in ribonucleotide reductase function. | 0.999 |
nrdH | CAR18984.1 | ECIAI39_2863 | ECIAI39_2862 | Glutaredoxin-like protein; Function experimentally demonstrated in the studied species; putative carrier. | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.478 |