STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygcWPutative deoxygluconate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (261 aa)    
Predicted Functional Partners:
ygcU
Putative FAD containing dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   0.829
nuoC
NADH:ubiquinone oxidoreductase, chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.658
kduI
5-keto 4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
 
  
 0.656
ygcQ
Putative flavoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
 
   0.525
ygcR
Putative flavoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
 
   0.522
ygcS
Putative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
     0.485
ygcE
Fragment of putative transporter (part 2); Gene remnant; putative transporter.
  
    0.422
entB
Isochorismatase; Function experimentally demonstrated in the studied species; enzyme.
  
  
 0.421
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.