node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM7 | PKH_010380 | A0A384KM50 | A0A384KVF9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 2, putative. | 0.998 |
MCM7 | PKH_040420 | A0A384KM50 | A0A384K9Y4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 5, putative. | 0.991 |
MCM7 | PKH_052040 | A0A384KM50 | A0A384KHQ9 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor, putative; Belongs to the MCM family. | 0.999 |
MCM7 | PKH_100500 | A0A384KM50 | A0A384KZ43 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM3, putative; Belongs to the MCM family. | 0.999 |
MCM7 | PKH_103030 | A0A384KM50 | A0A384KMW6 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | AAA domain-containing protein. | 0.999 |
MCM7 | PKH_121880 | A0A384KM50 | A0A384L200 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Uncharacterized protein. | 0.988 |
MCM7 | PKH_130180 | A0A384KM50 | A0A384LJB2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.995 |
MCM7 | PKH_131030 | A0A384KM50 | B3LBA1 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome mainoenance protein, putative; Belongs to the MCM family. | 0.991 |
MCM7 | PKH_131065 | A0A384KM50 | B3LBA5 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor MCM5, putative; Belongs to the MCM family. | 0.999 |
MCM7 | PKH_141630 | A0A384KM50 | A0A384KFX4 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA replication licensing factor mcm4-related,putative; Belongs to the MCM family. | 0.999 |
PKH_010380 | MCM7 | A0A384KVF9 | A0A384KM50 | Origin recognition complex subunit 2, putative. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.998 |
PKH_010380 | PKH_040420 | A0A384KVF9 | A0A384K9Y4 | Origin recognition complex subunit 2, putative. | Origin recognition complex subunit 5, putative. | 0.999 |
PKH_010380 | PKH_052040 | A0A384KVF9 | A0A384KHQ9 | Origin recognition complex subunit 2, putative. | DNA replication licensing factor, putative; Belongs to the MCM family. | 0.999 |
PKH_010380 | PKH_100500 | A0A384KVF9 | A0A384KZ43 | Origin recognition complex subunit 2, putative. | DNA replication licensing factor MCM3, putative; Belongs to the MCM family. | 0.999 |
PKH_010380 | PKH_103030 | A0A384KVF9 | A0A384KMW6 | Origin recognition complex subunit 2, putative. | AAA domain-containing protein. | 0.999 |
PKH_010380 | PKH_121880 | A0A384KVF9 | A0A384L200 | Origin recognition complex subunit 2, putative. | Uncharacterized protein. | 0.999 |
PKH_010380 | PKH_130180 | A0A384KVF9 | A0A384LJB2 | Origin recognition complex subunit 2, putative. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.999 |
PKH_010380 | PKH_131030 | A0A384KVF9 | B3LBA1 | Origin recognition complex subunit 2, putative. | Minichromosome mainoenance protein, putative; Belongs to the MCM family. | 0.944 |
PKH_010380 | PKH_131065 | A0A384KVF9 | B3LBA5 | Origin recognition complex subunit 2, putative. | DNA replication licensing factor MCM5, putative; Belongs to the MCM family. | 0.999 |
PKH_010380 | PKH_141630 | A0A384KVF9 | A0A384KFX4 | Origin recognition complex subunit 2, putative. | DNA replication licensing factor mcm4-related,putative; Belongs to the MCM family. | 0.996 |