STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKH_102410Single-stranded DNA-binding protein, putative. (280 aa)    
Predicted Functional Partners:
PKH_120680
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 
 0.869
PKH_031540
40S ribosomal protein S5, putative; Belongs to the universal ribosomal protein uS7 family.
  
   0.827
PKH_061110
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
   
   0.789
PKH_080220
40S ribosomal protein S20e, putative.
   
 
 0.766
PKH_124510
Ribosomal protein S10, apicoplast, putative.
   
 
 0.766
PKH_094090
Translation initiation factor eif-1a, Putative; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
   
  
 0.741
PKH_132040
ADP-dependent DNA helicase RecQ, putative.
   
 
 0.734
PKH_020730
Dna binding protein, putative.
   
 
 0.734
PKH_050340
Ribosomal protein L21, apicoplast, putative.
   
  
 0.732
PKH_132700
Ribosomal protein, putative.
   
  
 0.732
Your Current Organism:
Plasmodium knowlesi
NCBI taxonomy Id: 5851
Other names: P. knowlesi strain H, Plasmodium knowlesi (STRAIN H), Plasmodium knowlesi H, Plasmodium knowlesi Malayan H, Plasmodium knowlesi strain H
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.