STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKH_133730Rhoptry associated protein, putative. (782 aa)    
Predicted Functional Partners:
PKH_072840
Merozoite surface protein 1 paralog.
    
 
 0.702
PKH_010540
Rhoptry associated membrane antigen, RAMA.
      
 0.685
PKH_120680
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
      
 0.588
PKH_083050
SECIS-binding protein 2, putative.
    
 0.554
PKH_123270
Protein disulfide-isomerase, putative.
    
 0.554
PKH_050300
Protein disulfide-isomerase.
    
 0.554
PKH_071660
Protein disulfide isomerase, putative.
    
 0.554
PKH_092520
Protein disulfide-isomerase, putative.
    
 0.554
PKH_120150
Thioredoxin-related protein, putative.
    
 0.554
PKH_093110
Apical merozoite antigen 1.
      
 0.525
Your Current Organism:
Plasmodium knowlesi
NCBI taxonomy Id: 5851
Other names: P. knowlesi strain H, Plasmodium knowlesi (STRAIN H), Plasmodium knowlesi H, Plasmodium knowlesi Malayan H, Plasmodium knowlesi strain H
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.