Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95171.1Hypothetical protein; COG2768 Uncharacterized Fe-S center protein. (321 aa)    
Predicted Functional Partners:
AEN95172.1
Hypothetical protein.
       0.685
AEN95168.1
ABC sugar transporter, inner membrane subunit; COG1175 ABC-type sugar transport systems, permease components.
       0.538
AEN95169.1
COG0395 ABC-type sugar transport system, permease component.
       0.538
AEN95170.1
Neopullulanase; COG0366 Glycosidases.
       0.538
AEN96310.1
COG4624 Iron only hydrogenase large subunit, C-terminal domain.
   
 
 0.517
AEN96981.1
COG1142 Fe-S-cluster-containing hydrogenase components 2.
   
 
 0.517
AEN97047.1
Transcriptional regulator; COG4624 Iron only hydrogenase large subunit, C-terminal domain.
   
 
 0.517
larC
Hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
    0.507
AEN95173.1
Hypothetical protein; COG0534 Na+-driven multidrug efflux pump.
  
    0.456
AEN96087.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
  
    0.432
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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