Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN95201.1COG2357 Uncharacterized protein conserved in bacteria. (231 aa)    
Predicted Functional Partners:
AEN97980.1
RelA/SpoT domain-containing protein; COG2357 Uncharacterized protein conserved in bacteria.
  
  
 
0.919
AEN95848.1
GTP pyrophosphokinase; COG2357 Uncharacterized protein conserved in bacteria.
  
  
 
0.912
AEN97439.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.910
AEN95750.1
Adenylate cyclase; COG2954 Uncharacterized protein conserved in bacteria.
     
  0.900
AEN96093.1
COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase.
     
  0.900
AEN96740.1
COG0248 Exopolyphosphatase.
     
  0.900
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
  0.800
AEN95199.1
Lysophospholipase L2 PLDB, hydrolase of alpha/beta superfamily protein; COG2267 Lysophospholipase.
  
    0.786
AEN95198.1
COG0584 Glycerophosphoryl diester phosphodiesterase.
       0.781
AEN95200.1
Hypothetical protein; COG2270 Permeases of the major facilitator superfamily.
       0.773
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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