Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95221.1Glycoside hydrolase family protein; COG5434 Endopolygalacturonase; Belongs to the glycosyl hydrolase 28 family. (382 aa)    
Predicted Functional Partners:
AEN96572.1
Glucosyl hydrolase family protein; COG4225 Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins.
   
 0.938
AEN98064.1
Pectinesterase; COG4677 Pectin methylesterase.
 
   
 0.813
AEN95222.1
Hypothetical protein.
       0.773
kduI
5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
   
 0.752
AEN96278.1
Alpha-glucuronidase Gh115A.
 
 
 0.584
AEN96747.1
Xylose isomerase domain-containing protein; COG1082 Sugar phosphate isomerases/epimerases.
 
     0.579
AEN95220.1
Hypothetical protein; COG0679 Predicted permeases.
       0.510
AEN95219.1
Hypothetical protein; COG1802 Transcriptional regulators.
     
 0.503
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
    0.454
AEN95224.1
Hypothetical protein.
       0.451
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.