Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95243.1Transmembrane ATP-binding protein ABC transporter; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. (139 aa)    
Predicted Functional Partners:
AEN95244.1
Hypothetical protein; COG0842 ABC-type multidrug transport system, permease component.
       0.773
AEN95667.1
ABC transporter ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.
 
 
   0.760
AEN98348.1
Lipid A export ATP-binding/permease MsbA; COG1132 ABC-type multidrug transport system, ATPase and permease components.
  
     0.701
AEN95768.1
ABC transporter ATP-binding protein/permease; COG1132 ABC-type multidrug transport system, ATPase and permease components.
  
     0.562
AEN95242.1
MATE efflux family protein; COG0534 Na+-driven multidrug efflux pump.
  
    0.545
AEN96063.1
ATP-binding cassette subfamily C protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.
  
     0.474
AEN95665.1
Bacitracin ABC transporter ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.
  
  0.469
AEN96851.1
ABC transporter ATP-binding protein/permease; COG1132 ABC-type multidrug transport system, ATPase and permease components.
  
     0.441
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
     0.438
AEN95245.1
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
    0.427
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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