Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fliWFlagellar assembly factor fliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (153 aa)    
Predicted Functional Partners:
csrA
Putative carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
 
 
 0.999
AEN95253.1
Flagellar hook-associated protein 3; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.984
AEN95256.1
COG1334 Uncharacterized flagellar protein FlaG.
  
  
 0.970
AEN95258.1
Flagellar protein FliS; COG1516 Flagellin-specific chaperone FliS.
 
  
 0.941
AEN95257.1
COG1345 Flagellar capping protein.
 
  
 0.928
AEN95252.1
COG1256 Flagellar hook-associated protein; Belongs to the flagella basal body rod proteins family.
 
  
 0.914
AEN95251.1
COG1256 Flagellar hook-associated protein; Belongs to the flagella basal body rod proteins family.
 
  
 0.900
AEN96516.1
COG1868 Flagellar motor switch protein.
 
  
 0.896
AEN96517.1
Flagellar motor switch protein; COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation.
 
  
 0.893
AEN95260.1
Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.886
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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