STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEN95345.1Hypothetical RNA methyltransferase-like protein; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (474 aa)    
Predicted Functional Partners:
AEN95344.1
COG3481 Predicted HD-superfamily hydrolase.
       0.777
AEN97270.1
RNA methyltransferase.
 
      0.751
AEN95343.1
COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.
  
    0.664
AEN97757.1
RNA methyltransferase.
 
      0.627
mutS2
DNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
    0.517
rsmI
Tetrapyrrole (corrin/porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
  
 0.509
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
 
   
 0.480
AEN97112.1
16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.430
AEN95347.1
COG0286 Type I restriction-modification system methyltransferase subunit.
       0.407
AEN96337.1
Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.407
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.