Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95397.1Metal dependent phosphohydrolase; COG2206 HD-GYP domain. (352 aa)    
Predicted Functional Partners:
AEN95600.1
Hypothetical protein; COG2206 HD-GYP domain.
  
     0.770
AEN95402.1
Hypothetical protein; COG2199 FOG: GGDEF domain.
   0.759
AEN95559.1
Signaling protein; COG2199 FOG: GGDEF domain.
 
 
 0.738
AEN96871.1
Sensory transduction system regulatory protein; COG2199 FOG: GGDEF domain.
  
   0.707
AEN95398.1
Hypothetical protein; COG1309 Transcriptional regulator.
       0.705
AEN97885.1
Diguanylate cyclase; COG2199 FOG: GGDEF domain.
  
   0.705
AEN96129.1
Putative regulatory components of sensory transduction system; COG2199 FOG: GGDEF domain.
  
   0.704
AEN97886.1
Diguanylate cyclase; COG2199 FOG: GGDEF domain.
  
   0.704
AEN96086.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COG2199 FOG: GGDEF domain.
 
 
 0.698
AEN96422.1
PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase; COG2199 FOG: GGDEF domain.
  
   0.697
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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