Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95502.1Hypothetical protein; COG0358 DNA primase (bacterial type). (1094 aa)    
Predicted Functional Partners:
AEN95501.1
Hypothetical protein; COG0334 Glutamate dehydrogenase/leucine dehydrogenase.
 
     0.946
AEN95503.1
Hypothetical protein.
 
     0.946
AEN95500.1
DNA topoisomerase III; COG0550 Topoisomerase IA.
 
  
 0.909
AEN95499.1
Hypothetical protein.
 
     0.870
AEN95498.1
Hypothetical protein.
 
     0.863
AEN95497.1
DNA-repair protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).
 
     0.853
AEN95494.1
Hypothetical protein; COG0477 Permeases of the major facilitator superfamily.
 
     0.807
AEN95509.1
Hypothetical protein.
     0.787
AEN95512.1
Hypothetical protein; COG0841 Cation/multidrug efflux pump.
  
     0.773
AEN95514.1
Relaxase/mobilization nuclease family protein.
  
    0.770
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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