Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95518.1COG0642 Signal transduction histidine kinase. (350 aa)    
Predicted Functional Partners:
AEN95517.1
Regulatory protein VanR; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.954
AEN95520.1
Efflux ABC transporter permease; COG0577 ABC-type antimicrobial peptide transport system, permease component.
 
   
 0.871
AEN95519.1
ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.
 
     0.818
AEN97806.1
Regulatory protein VanR; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.806
AEN96407.1
Regulatory protein VanR; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
   0.805
AEN98349.1
Hypothetical protein; COG0577 ABC-type antimicrobial peptide transport system, permease component.
 
   
 0.754
AEN96410.1
Hypothetical protein; COG0577 ABC-type antimicrobial peptide transport system, permease component.
 
     0.706
AEN96409.1
Macrolide export ATP-binding/permease MacB; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.
 
     0.674
AEN97804.1
Macrolide export ATP-binding/permease MacB; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.
 
     0.671
AEN95516.1
Hypothetical protein.
   
 
 0.637
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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