STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN95549.1COG0492 Thioredoxin reductase. (288 aa)    
Predicted Functional Partners:
AEN95550.1
COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
 
 
 0.945
AEN96902.1
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
 
 
 0.938
AEN97149.1
Cysteine desulfurase, SufS subfamily protein; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 
  0.916
AEN95548.1
COG0386 Glutathione peroxidase.
  
  
 0.774
AEN95551.1
Peroxiredoxin; COG0386 Glutathione peroxidase.
  
  
 0.764
AEN95552.1
COG1846 Transcriptional regulators.
 
     0.702
AEN97938.1
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
 
 
 0.677
AEN95547.1
Hypothetical protein.
       0.668
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.509
AEN98112.1
Hypothetical protein.
  
  
 0.494
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.