STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN95561.1Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (253 aa)    
Predicted Functional Partners:
AEN95560.1
COG1882 Pyruvate-formate lyase.
  
 0.989
AEN96922.1
COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase.
   
    0.812
AEN95562.1
COG0840 Methyl-accepting chemotaxis protein.
       0.693
AEN96093.1
COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase.
 
  
 0.564
AEN95869.1
NADPH-dependent butanol dehydrogenase; COG1454 Alcohol dehydrogenase, class IV.
 
  
 0.519
AEN95563.1
Hypothetical protein.
       0.517
AEN96087.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.503
AEN95190.1
COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
 
   
 0.492
AEN95660.1
L-1,2-propanediol oxidoreductase; COG1454 Alcohol dehydrogenase, class IV.
  
  
 0.454
AEN96982.1
COG1454 Alcohol dehydrogenase, class IV.
  
  
 0.454
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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