STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiAHypothetical protein; Involved in cell division and chromosome segregation. (289 aa)    
Predicted Functional Partners:
AEN95620.1
glmZ(sRNA)-inactivating NTPase; Displays ATPase and GTPase activities.
 
  
 0.869
murB
Hypothetical protein; Cell wall formation.
 
   
 0.836
AEN95622.1
COG1925 Phosphotransferase system, HPr-related proteins.
  
  
 0.731
AEN95623.1
Putative lipid kinase; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.
       0.673
AEN97072.1
Hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
  
 0.650
AEN96213.1
COG4472 Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family.
  
     0.641
AEN96108.1
Hypothetical protein; COG2384 Predicted SAM-dependent methyltransferase.
  
     0.635
AEN97109.1
COG0515 Serine/threonine protein kinase.
 
   
 0.625
hprK
HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...]
     
 0.609
AEN96882.1
COG1302 Uncharacterized protein conserved in bacteria.
  
     0.605
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.